Frovatriptan-d3 (succinate)
Frovatriptan-d3 (succinate)
SKU:QM-0159990-01
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Product Details
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Description
Frovatriptan-d3 (succinate) is deuterium labeled Frovatriptan (succinate) . Frovatriptan succinate ((R) -Frovatriptan succinate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate has the potential for migraine research[1][2].
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Molecular Formula
C18H20D3N3O5
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Molecular Weight
364.41
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Smiles
[2H]C([2H])([2H])N[C@@H](C1)CCC2=C1C(C=C(C(N)=O)C=C3)=C3N2.OC(CCC(O)=O)=O
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Target
5-HT Receptor; Isotope-Labeled Compounds
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Isoform
5-HT1 Receptor;5-HT7 Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Frovatriptan-d3 (succinate)
Frovatriptan-d3 (succinate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.