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Frovatriptan (succinate) [CAS 158930-09-7]

Frovatriptan (succinate) [CAS 158930-09-7]

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SKU:QM-0118294

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  • Description

    Frovatriptan succinate ((R) -Frovatriptan succinate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate has the potential for migraine research[1][2].

  • CAS Number

    [158930-09-7]

  • Molecular Formula

    C18H23N3O5

  • Molecular Weight

    361.39

  • Smiles

    O=C(O)CCC(O)=O.O=C(C1=CC2=C(NC3=C2C[C@H](NC)CC3)C=C1)N

  • Target

    5-HT Receptor

  • Isoform

    5-HT1 Receptor;5-HT7 Receptor; mLAG-3

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302-H312-H332

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Frovatriptan (succinate) [CAS 158930-09-7]

Frovatriptan (succinate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.