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G4/HDAC-IN-1 [CAS 3031784-60-5]
G4/HDAC-IN-1 [CAS 3031784-60-5]
SKU:QM-0069268
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Product Details
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Description
G4/HDAC-IN-1 (compound a6) is a G4/HDAC dual-targeting compound. G4/HDAC-IN-1 inhibits intracellular HDAC activity with an IC50 value of 1.1 μM, and induces G4 formation. G4/HDAC-IN-1 inhibits TNBC proliferation and tumor growth in TNBC xenograft model. G4/HDAC-IN-1 can be used for the research of cancer[1].
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CAS Number
[3031784-60-5]
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Molecular Formula
C36H49ClFN7O4
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Molecular Weight
698.27
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Smiles
O=C(NCCCN(C)C)C1=CC=C(/C=C2CCN3C\2=NC4=C(C=C(F)C(N5CCN(CCCCCCCC(NO)=O)CC5)=C4)C3=O)C=C1.Cl
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Target
G-quadruplex; HDAC
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Isoform
HDAC1; HDAC11; HDAC4; HDAC6; HDAC8
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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G4/HDAC-IN-1 [CAS 3031784-60-5]
G4/HDAC-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.