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GBR 12935 (fumarate) [CAS 1349767-56-1]
GBR 12935 (fumarate) [CAS 1349767-56-1]
SKU:QM-0093420
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Product Details
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Description
GBR 12935 fumarate is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 fumarate stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 fumarate also prevents the d-Fenfluramine-induced head-twitch response in mice[1][2][3][4].
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CAS Number
[1349767-56-1]
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Molecular Formula
C32H38N2O5
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Molecular Weight
530.65
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Smiles
O=C(O)/C=C\C(O)=O.N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(CCCC4=CC=CC=C4)CC1
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Target
Dopamine Transporter
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P280-P302+P352
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GBR 12935 (fumarate) [CAS 1349767-56-1]
GBR 12935 (fumarate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.