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Gefitinib-d3 [CAS 1173976-40-3]

Gefitinib-d3 [CAS 1173976-40-3]

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SKU:QM-0074397

£771.71 GBP
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  • Description

    Gefitinib-d3 (ZD1839-d3) is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].

  • CAS Number

    [1173976-40-3]

  • Molecular Formula

    C22H21D3ClFN4O3

  • Molecular Weight

    449.92

  • Smiles

    N(C=1C2=C(C=C(OC([2H])([2H])[2H])C(OCCCN3CCOCC3)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4

  • Target

    Autophagy; EGFR; Isotope-Labeled Compounds

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Gefitinib-d3 [CAS 1173976-40-3]

Gefitinib-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.