Gefitinib (hydrochloride) (Standard) [CAS 184475-55-6]
Gefitinib (hydrochloride) (Standard) [CAS 184475-55-6]
SKU:QM-0017455-01
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Product Details
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Description
Gefitinib (hydrochloride) (Standard) is the analytical standard of Gefitinib (hydrochloride) . This product is intended for research and analytical applications. Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity[1][2].
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CAS Number
[184475-55-6]
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Molecular Formula
C22H25Cl2FN4O3
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Molecular Weight
483.36
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Smiles
ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F.[H]Cl
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Target
EGFR; Reference Standards
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Shipping Conditions
Room temperature
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Gefitinib (hydrochloride) (Standard) [CAS 184475-55-6]
Gefitinib (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.