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Glafenine (hydrochloride) [CAS 65513-72-6]

Glafenine (hydrochloride) [CAS 65513-72-6]

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SKU:QM-0159431-01

£94.75 GBP
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  • Description

    Glafenine (Glafenin) hydrochloride is a non-selective, non-steroidal anti-inflammatory drug-based COX-1/COX-2 inhibitor. Glafenine hydrochloride exerts anti-inflammatory, anti-proliferative and anti-cell migration effects by inhibiting the arachidonic acid metabolic pathway and reducing prostaglandin synthesis. Glafenine hydrochloride can induce cell cycle arrest in vascular smooth muscle cells and endothelial cells and reduce the synthesis of the extracellular matrix protein Tenascin. Glafenine hydrochloride can be used in the research of inflammatory-related diseases, vascular restenosis and cystic fibrosis (CF) [1][2][3][4].

  • CAS Number

    [65513-72-6]

  • Molecular Formula

    C19H18Cl2N2O4

  • Molecular Weight

    409.26

  • Smiles

    [H]Cl.O=C(OCC(O)CO)C1=CC=CC=C1NC2=CC=NC3=CC(Cl)=CC=C23

  • Target

    Apoptosis; CFTR; COX; Endoplasmic Reticulum Oxidoreductase 1 (ERO1)

  • Isoform

    COX-1; COX-2

  • Concentration

    10mM

  • Purity

    99.03

  • Solubility

    DMSO : 41.67 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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100 mgQM-0159431-01
100 mgQM-0159431-01
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10 mM - 1 mLQM-0159431-02
10 mM - 1 mLQM-0159431-02
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Glafenine (hydrochloride) [CAS 65513-72-6]

Glafenine (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.