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GSK 1842799 (hydrochloride) [CAS 1277165-15-7]

GSK 1842799 (hydrochloride) [CAS 1277165-15-7]

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SKU:QM-0091502

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  • Description

    GSK 1842799 hydrochloride is a selective S1P1 receptor agonist with potent agonist activity and exceptional selectivity over S1P3. GSK 1842799 hydrochloride demonstrates good oral bioavailability and rapid conversion to its active phosphorylated form. GSK 1842799 hydrochloride significantly reduces blood lymphocyte counts in vivo following oral administration. GSK 1842799 hydrochloride has shown efficacy comparable to FTY720 in the mouse EAE model of multiple sclerosis.

  • CAS Number

    [1277165-15-7]

  • Molecular Formula

    C20H30Cl2F3N3O2S

  • Molecular Weight

    504.44

  • Smiles

    OC[C@](N)(C1=NN=C(C2=CC(C(F)(F)F)=C(C=C2)OCCCCCCCC)S1)C.Cl.Cl

  • Target

    Endogenous Metabolite

  • Shipping Conditions

    Room temperature

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GSK 1842799 (hydrochloride) [CAS 1277165-15-7]

GSK 1842799 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.