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GSK-3β/HDAC-IN-1
GSK-3β/HDAC-IN-1
SKU:QM-0104947
Price on request
Quantity
Request quote or documents
Product Details
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Description
GSK-3β/HDAC-IN-1 (Compd 4) is a brain-penetrant and first in class dual non-ATP-competitive Glycogen Synthase Kinase 3β/Histone Deacetylases (GSK-3β/HDACs) Inhibitor with IC50s of 0.142, 0.03 and 0.045 μM against GSK-3β, HDAC2 and HDAC6, respectively. GSK-3β/HDAC-IN-1 can be used for Alzheimer’s disease research[1].
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Molecular Formula
C20H15N3O4S
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Molecular Weight
393.42
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Smiles
O=C(NO)C1=CC=C(CN2C(SN(C3=C(C=CC=C4)C4=CC=C3)C2=O)=O)C=C1
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Target
GSK-3; HDAC
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Isoform
GSK-3β; HDAC2; HDAC6
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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GSK-3β/HDAC-IN-1
GSK-3β/HDAC-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.