GTS-21 (dihydrochloride) [CAS 156223-05-1]
GTS-21 (dihydrochloride) [CAS 156223-05-1]
SKU:QM-0148655-01
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Product Details
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Description
GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti inflammatory and cognition enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist[1][2].
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CAS Number
[156223-05-1]
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Molecular Formula
C19H22Cl2N2O2
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Molecular Weight
381.3
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Smiles
COC1=CC(OC)=CC=C1/C=C2CCCN=C\2C3=CC=CN=C3.Cl[H].Cl[H]
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Target
5-HT Receptor; nAChR
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Isoform
5-HT3 Receptor; lactoferrin
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Purity
99.65
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Solubility
DMSO : 16.5 mg/mL (ultrasonic; warming) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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GTS-21 (dihydrochloride) [CAS 156223-05-1]
GTS-21 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.