Gymnemic acid I [CAS 122168-40-5]
Gymnemic acid I [CAS 122168-40-5]
SKU:QM-0165031-01
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Product Details
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Description
Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I is an antisweetness inhibitor via human sweet receptor type 1 receptor 2 (T1R2) and T1R3. Gymnemic acid I is a ribosomal protein biosynthesis inhibitor. Gymnemic acid I has antidiabetic effects. Gymnema acid I induces autophagy-protected MIN-6 cells from apoptosis under high glucose stress by inhibiting the phosphorylation activity of mTOR[1][2].
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CAS Number
[122168-40-5]
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Molecular Formula
C43H66O14
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Molecular Weight
806.98
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Smiles
O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1O[C@@H]2CC[C@]3(C)[C@@]4([H])CC=C5[C@]6([H])CC(C)(C)[C@H](OC(/C(C)=C/C)=O)[C@@H](O)[C@@](COC(C)=O)6[C@H](O)C[C@](C)5[C@@](C)4CC[C@]([H])3[C@@]2(C)CO
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Target
Apoptosis; Autophagy; mTOR; Taste Receptor
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Purity
99.79
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, protect from light)
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Shipping Conditions
Blue Ice
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Hazard Statement
H315-H319-H335
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Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
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Gymnemic acid I [CAS 122168-40-5]
Gymnemic acid I is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.