HA-1004 di (hydrochloride) [CAS 92564-08-4]
HA-1004 di (hydrochloride) [CAS 92564-08-4]
SKU:QM-0094010
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Product Details
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Description
HA-1004 dihydrochloride is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 dihydrochloride is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein, and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 dihydrochloride is an antagonist for calcium, that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models[1][2][3].
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CAS Number
[92564-08-4]
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Molecular Formula
C12H17Cl2N5O2S
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Molecular Weight
366.27
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Smiles
O=S(C1=CC=CC2=C1C=CN=C2)(NCCNC(N)=N)=O.[H]Cl.[H]Cl
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Target
Calcium Channel; Cyclic GMP-AMP Synthase; ERK; PKA; Tyrosine Hydroxylase
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Shipping Conditions
Room temperature
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HA-1004 di (hydrochloride) [CAS 92564-08-4]
HA-1004 di (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.