Skip to product information
1 of 1

HCA/VEGFR-2-IN-3 [CAS 2971782-73-5]

HCA/VEGFR-2-IN-3 [CAS 2971782-73-5]

Size

SKU:QM-0072029

Price on request
Quantity

Request quote or documents

View full details
  • Description

    HCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide and a potential dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. hCA/VEGFR-2-IN-3 inhibits VEGFR-2 (IC50=358 nM), has high binding activity to hCAs with Ki of 4.2 nM (hCA IX), 22.9 nM (hCA II), 25.1 nM (hCA I), 28.0 nM (hCA XII), respectively. hCA/VEGFR-2-IN-3 has antiproliferative activity against VEGFR-2 overexpressing breast cancer cells[1].

  • CAS Number

    [2971782-73-5]

  • Molecular Formula

    C24H28N6O6S

  • Molecular Weight

    528.58

  • Smiles

    CC(N1CC(C(N/N=C2C(NC3=C\2C=C(OC)C=C3)=O)=O)CCC1)C(NC4=CC=C(S(=O)(N)=O)C=C4)=O

  • Target

    Carbonic Anhydrase; VEGFR

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

Your cart
Variant Variant total Quantity Price Variant total
1 EachQM-0072029
1 EachQM-0072029
£0.00/ea
£0.00
£0.00/ea £0.00

HCA/VEGFR-2-IN-3 [CAS 2971782-73-5]

HCA/VEGFR-2-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.