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HDAC degrader-2
HDAC degrader-2
SKU:QM-0015036
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Product Details
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Description
HDAC degrader-2 is a selective HDAC degrader with a DC50 values of 2.55 μM against HDAC1. HDAC degrader-2 effectively induces the degradation of HDAC1 and HDAC2, but has no significant effect on the degradation of HDAC3, 4, 6 and 8. HDAC degrader-2 exerts potent antiproliferative effects against MM.1S and MCF-7 cells. HDAC degrader-2 induces apoptosis in myeloma cells. HDAC degrader-2 can be used for the study of myeloma[1].
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Molecular Formula
C32H35ClN4O5
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Molecular Weight
591.1
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Smiles
O=C(NCCCCCCC(NO)=O)C1=CC=C(C2CC(C3=CC=CC(OCC4=CC=CC=C4)=C3)=NN2C(CCl)=O)C=C1
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Target
Apoptosis; HDAC
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Isoform
HDAC1; HDAC2
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Shipping Conditions
Room temperature
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HDAC degrader-2
HDAC degrader-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.