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HDAC/HSP90-IN-3 [CAS 2700035-54-5]
HDAC/HSP90-IN-3 [CAS 2700035-54-5]
SKU:QM-0065938
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Product Details
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Description
HDAC/HSP90-IN-3 (compound J5) is a potent and selective fungal Hsp90 and HDAC dual inhibitor, with IC50 values of 0.83 and 0.91 μM, respectively. HDAC/HSP90-IN-3 shows antifungal activity against azole resistant C. albicans. HDAC/HSP90-IN-3 can suppress important virulence factors and down-regulate drug-resistant genes ERG11 and CDR1[1].
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CAS Number
[2700035-54-5]
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Molecular Formula
C26H33N5O6
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Molecular Weight
511.57
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Smiles
CC(C1=CC(C2=NNC(N2C3=CC=C(C=C3)C(NCCCCCCCC(NO)=O)=O)=O)=C(C=C1O)O)C
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Target
Fungal; HDAC; HSP
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Isoform
HDAC; HSP90
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HDAC/HSP90-IN-3 [CAS 2700035-54-5]
HDAC/HSP90-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.