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HDAC-IN-34 [CAS 2857097-33-5]
HDAC-IN-34 [CAS 2857097-33-5]
SKU:QM-0065178
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Product Details
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Description
HDAC-IN-34 (compound 27) is a potent HDAC inhibitor, with IC50 values of 0.022 and 0.45 μM for HDAC1 and HDAC6, respectively. HDAC-IN-34 can bind to DNA and cause DNA damage. HDAC-IN-34 causes cells apoptosis through p53 signaling pathway. HDAC-IN-34 exhibits significant anti-proliferation effect against HCT-116 cells, with an IC50 of 1.41 μM[1].
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CAS Number
[2857097-33-5]
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Molecular Formula
C24H26N6O3
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Molecular Weight
446.5
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Smiles
COC1=CC2=C(C3=C(N2CC4CCN(CC4)C5=NC=C(C=N5)C(NO)=O)C(C)=NC=C3)C=C1
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Target
Apoptosis; HDAC; MDM-2/p53
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Isoform
HDAC1; HDAC6
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HDAC-IN-34 [CAS 2857097-33-5]
HDAC-IN-34 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.