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HDAC-IN-53 [CAS 2921948-27-6]

HDAC-IN-53 [CAS 2921948-27-6]

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QM-0068190-01

£652.64 GBP
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Product Details

  • Description

    HDAC-IN-53 is an orally active, and selective HDAC1-3 inhibitor with IC50 values of 47 nM, 125 nM, and 450 nM, respectively. HDAC-IN-53 does not inhibit class II HDACs (HDAC4, 5, 6, 7, 9; IC50>10 μM) . HDAC-IN-53 induces caspase-dependent apoptosis. HDAC-IN-53 significantly inhibits the growth of human tumor xenografts in nude mice and murine tumor growth in immune-competent mice bearing MC38 colon cancer[1].

  • CAS Number

    [2921948-27-6]

  • Molecular Formula

    C23H20ClN7O2

  • Molecular Weight

    461.9

  • Smiles

    NC1=NN(C2=CC=CC=C2Cl)N=C1C(NCC3=CC=C(C=C3)C(NC4=CC=CC=C4N)=O)=O

  • Target

    Apoptosis; HDAC

  • Isoform

    HDAC1; HDAC2; HDAC3; HDAC4; HDAC5; HDAC6; HDAC7; HDAC8; HDAC9

  • Purity

    95.73

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0068190-01
1 mgQM-0068190-01
£652.64/ea		 £0.00
£652.64/ea £0.00
5 mgQM-0068190-02
5 mgQM-0068190-02
£1,556.60/ea		 £0.00
£1,556.60/ea £0.00
10 mgQM-0068190-03
10 mgQM-0068190-03
£2,460.56/ea		 £0.00
£2,460.56/ea £0.00
25 mgQM-0068190-04
25 mgQM-0068190-04
£4,869.90/ea		 £0.00
£4,869.90/ea £0.00
50 mgQM-0068190-05
50 mgQM-0068190-05
£7,280.47/ea		 £0.00
£7,280.47/ea £0.00
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HDAC-IN-53 [CAS 2921948-27-6]

HDAC-IN-53 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.