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HDAC-IN-57 [CAS 2716217-79-5]
HDAC-IN-57 [CAS 2716217-79-5]
SKU:QM-0068713-01
£499.55 GBP
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Product Details
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Description
HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. HDAC-IN-57 can inhibits LSD1, with IC50 of 1.34 μΜ. HDAC-IN-57 induces apoptosis, and has anti-tumor activity[1].
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CAS Number
[2716217-79-5]
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Molecular Formula
C21H19N3O4
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Molecular Weight
377.39
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Smiles
O=C(C1=CC=C(CNC(C2=CC(C3=CC=C(OC)C=C3)=NC=C2)=O)C=C1)NO
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Target
Apoptosis; HDAC; Histone Demethylase
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Isoform
HDAC1; HDAC2; HDAC6; HDAC8
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HDAC-IN-57 [CAS 2716217-79-5]
HDAC-IN-57 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.