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HDAC-IN-63 [CAS 2920046-95-1]

HDAC-IN-63 [CAS 2920046-95-1]

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SKU:QM-0068393

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  • Description

    HDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor (IC50: 0.844 and 30.0 nM for FLT3 and HDAC1 respectively) . HDAC-IN-63 inhibits MV4-11 cell proliferation (IC50: 92 nM. HDAC-IN-63 induces apoptosis and arrests cell cycle in MV4-11 cells. HDAC-IN-63 can be used for research of acute myeloid leukemia (AML) [1].

  • CAS Number

    [2920046-95-1]

  • Molecular Formula

    C25H26Cl2N6O3

  • Molecular Weight

    529.42

  • Smiles

    ClC1=CC=CC(Cl)=C1CN(C=N2)C3=C2C=CC(C4=CC(NC(CCCCCCC(NO)=O)=O)=NN4)=C3

  • Target

    Apoptosis; FLT3; HDAC

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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HDAC-IN-63 [CAS 2920046-95-1]

HDAC-IN-63 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.