HDAC-IN-92
HDAC-IN-92
SKU:QM-0013477
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Product Details
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Description
HDAC-IN-92 is a pan-HDAC inhibitor with an IC50 of 12.58 µM in A2780 cells. HDAC-IN-92 demonstrates broad-spectrum, notable cytotoxic activity against a range of human cancer cell lines, including ovarian, liver, and breast carcinomas. HDAC-IN-92 causes apoptosis and demonstrates a notable decrease in tumor cell colony formation. HDAC-IN-92 inhibits the formation of blood vessels in the chick chorioallantoic membrane (CAM) . HDAC-IN-92 exhibits anti-tumor effect in a 4T1 tumor-bearing mouse model. HDAC-IN-92 can be used for research targeting solid tumor[1].
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Molecular Formula
C19H17FN4O2S
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Molecular Weight
384.43
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Smiles
O=C(NO)C1=CC=C(/N=C/C2=CN=C(SCC3=CC=CC(F)=C3)N2C)C=C1
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Target
Apoptosis; HDAC
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Shipping Conditions
Room temperature
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HDAC-IN-92
HDAC-IN-92 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.