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HDAC-IN-96 [CAS 3055552-13-8]

HDAC-IN-96 [CAS 3055552-13-8]

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SKU:QM-0014784

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  • Description

    HDAC-IN-96 (Compound 3f) is a selective HDAC1/2 inhibitor with IC50 values of 457.1 and 433.7 nM. HDAC-IN-96 has strong inhibitory activity against multiple hematological tumor cells (RS4;11, K562, RPMI-8226, U266), with IC50 values ranging from 2.11 to 5.35 μM. HDAC-IN-96 can induce cancer cells apoptosis and S phase arrest. HDAC-IN-96 can be used for the research of cancer, such as acute lymphoblastic leukemia[1].

  • CAS Number

    [3055552-13-8]

  • Molecular Formula

    C27H22FN5O5

  • Molecular Weight

    515.49

  • Smiles

    O=C(C1=CC=C(C=C1)CNC2=CC=CC(C(N3C4CCC(NC4=O)=O)=O)=C2C3=O)NC5=CC=C(C=C5N)F

  • Target

    Apoptosis; HDAC

  • Isoform

    HDAC1; HDAC2

  • Shipping Conditions

    Room temperature

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HDAC-IN-96 [CAS 3055552-13-8]

HDAC-IN-96 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.