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HDAC1/6-IN-1 [CAS 2630989-02-3]

HDAC1/6-IN-1 [CAS 2630989-02-3]

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SKU:QM-0065962

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  • Description

    HDAC1/6-IN-1 (compound D7) is a potent multitarget inhibitor of GLP, HDAC6 and HDAC1, with IC50 values of 1.3, 13, and 89 nM, respectively. HDAC1/6-IN-1 can inhibit the methylation and deacetylation of H3K9 on protein level. HDAC1/6-IN-1 induces cancer cell apoptosis, G0/G1 cell cycle arrest, and blocks migration and invasion[1].

  • CAS Number

    [2630989-02-3]

  • Molecular Formula

    C32H45N7O4

  • Molecular Weight

    591.74

  • Smiles

    COC1=C(C=C2C(N=C(N=C2NC3CCN(CC3)CC4=CC=CC=C4)N5CCN(CC5)CCCCCC(NO)=O)=C1)OC

  • Target

    Apoptosis; HDAC

  • Isoform

    HDAC1; HDAC6

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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HDAC1/6-IN-1 [CAS 2630989-02-3]

HDAC1/6-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.