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HDAC1-IN-9
HDAC1-IN-9
SKU:QM-0009749
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Product Details
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Description
HDAC1-IN-9 (13c) is a HDAC1 inhibitor. HDAC1-IN-9 inhibits HDAC1 enzyme with an IC50 of 1.07 µM. HDAC1-IN-9 exhibits the highest anti-proliferative effect against HT-29 (human colon adenocarcinoma), with anIC50 of 1.78 μM. HDAC1-IN-9 induces substantial Apoptosis in HCT-116 (human colon cancer) cells. HDAC1-IN-9 possesses antiangiogenic property. HDAC1-IN-9 reduces the expression levels of VEGFR-2 and phosphorylated VEGFR-2 (pVEGFR-2) by approximately 80 %[1].
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Molecular Formula
C17H17N3O3
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Molecular Weight
311.34
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Smiles
O=C(C1=C(C)NC(/C=C2C(NC3=C\2C=C(C)C=C3)=O)=C1C)NO
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Target
HDAC
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Isoform
HDAC1
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Shipping Conditions
Room temperature
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HDAC1-IN-9
HDAC1-IN-9 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.