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HDAC6 degrader-3 [CAS 2785404-83-1]

HDAC6 degrader-3 [CAS 2785404-83-1]

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QM-0150751-01

£963.68 GBP
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Product Details

  • Description

    HDAC6 degrader-3 is a potent and selective HDAC6 degrader via ternary complex formation and the ubiquitin-proteasome pathway with a DC50 value of 19.4 nM. HDAC6 degrader-3 has IC50s of 4.54 nM and 0.647 μM for HDAC6 and HDAC1, respectively. HDAC6 degrader-3 causes strong hyperacetylation of α-tubulin[1].

  • CAS Number

    [2785404-83-1]

  • Molecular Formula

    C41H41F4N7O11

  • Molecular Weight

    883.8

  • Smiles

    O=C(CCCCCCCNC(COC1=CC=CC(C(N2C3CCC(NC3=O)=O)=O)=C1C2=O)=O)NC4=CC5=C(C=C4)N(C(C)=N5)CC6=C(C=C(C=C6)C(NO)=O)F.FC(F)(F)C(O)=O

  • Target

    HDAC; PROTACs

  • Isoform

    Cereblon; HDAC1; HDAC6

  • Purity

    98.12

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Blue Ice
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Variant Variant total Quantity Price Variant total
5 mgQM-0150751-01
5 mgQM-0150751-01
£963.68/ea		 £0.00
£963.68/ea £0.00
10 mgQM-0150751-02
10 mgQM-0150751-02
£1,566.32/ea		 £0.00
£1,566.32/ea £0.00
25 mgQM-0150751-03
25 mgQM-0150751-03
£3,234.51/ea		 £0.00
£3,234.51/ea £0.00
50 mgQM-0150751-04
50 mgQM-0150751-04
£5,145.71/ea		 £0.00
£5,145.71/ea £0.00
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HDAC6 degrader-3 [CAS 2785404-83-1]

HDAC6 degrader-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.