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HDAC6-IN-28

HDAC6-IN-28

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SKU:QM-0072862

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  • Description

    HDAC6-IN-28 (compound 10C) is a potent inhibitor of HDAC6 with an IC50 of 261 nM. HDAC6-IN-28 significantly induces apoptosis and S-phase arrest in B16-F10 cells. HDAC6-IN-28 efficiently increases the expression of acetylated-α-tubulin in vitro and in vivo[1].

  • Molecular Formula

    C23H16FN3O2

  • Molecular Weight

    385.39

  • Smiles

    FC(N=C1C=CC=CC1=C23)=C3C4=CC=CC=C4N2CC5=CC=C(C=C5)C(NO)=O

  • Target

    Apoptosis; HDAC

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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HDAC6-IN-28

HDAC6-IN-28 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.