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Higenamine (hydrochloride) [CAS 11041-94-4]

Higenamine (hydrochloride) [CAS 11041-94-4]

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SKU:QM-0164623-01

£78.82 GBP
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  • Description

    Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases[1][2][3][4][5][6].

  • CAS Number

    [11041-94-4]

  • Molecular Formula

    C16H18ClNO3

  • Molecular Weight

    307.77

  • Smiles

    OC1=CC2=C(C(CC3=CC=C(O)C=C3)NCC2)C=C1O.[H]Cl

  • Target

    Apoptosis; MAP3K; MDM-2/p53; ROS Kinase

  • Isoform

    MAP3K5/ASK1; β adrenergic receptor

  • Purity

    99.52

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture and light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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100 mgQM-0164623-01
100 mgQM-0164623-01
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10 mM - 1 mLQM-0164623-02
10 mM - 1 mLQM-0164623-02
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500 mgQM-0164623-03
500 mgQM-0164623-03
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Higenamine (hydrochloride) [CAS 11041-94-4]

Higenamine (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.