HLI373 (dihydrochloride) [CAS 1782531-99-0]
HLI373 (dihydrochloride) [CAS 1782531-99-0]
SKU:QM-0136178-01
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Product Details
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Description
HLI373 dihydrochloride is an efficacious Hdm2 inhibitor. HLI373 dihydrochloride inhibits the ubiquitin ligase activity of Hdm2. HLI373 dihydrochloride is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents[1]. Antimalarial activity[2].
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CAS Number
[1782531-99-0]
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Molecular Formula
C18H25Cl2N5O2
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Molecular Weight
414.33
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Smiles
O=C1N=C2N(C)C3=C(C=CC=C3)C(NCCCN(C)C)=C2C(N1C)=O.[H]Cl.[H]Cl
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Target
Apoptosis; MDM-2/p53; Parasite
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Isoform
Plasmodium
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Purity
98.32
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Solubility
H2O : 38 mg/mL (ultrasonic; warming) |DMSO : 4 mg/mL (ultrasonic; warming)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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HLI373 (dihydrochloride) [CAS 1782531-99-0]
HLI373 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.