Hypidone (hydrochloride) [CAS 1339058-04-6]
Hypidone (hydrochloride) [CAS 1339058-04-6]
SKU:QM-0079670-01
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Product Details
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Description
Hypidone hydrochloride (YL0919) is an orally active antidepressant agent with dual activity as a highly seletive 5-HT uptake blocker and an effective 5-HT1A receptor agonist (Ki=0.19 nM) . Hypidone hydrochloride inhibits the uptake of [3H]-5-HT into rat cerebral cortical synaptosomes and HEK293 cells with IC50s of 1.78 nM and 1.93 nM, respectively. Hypidone hydrochloride shows remarkable antidepressant effects in animal models and has the poential for the investigation of depressive disorder[1].
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CAS Number
[1339058-04-6]
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Molecular Formula
C18H23ClN2O2
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Molecular Weight
334.84
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Smiles
O=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl
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Target
5-HT Receptor
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Isoform
5-HT1 Receptor; mLAG-3
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Purity
99.73
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Solubility
DMSO : ≥ 30 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Hypidone (hydrochloride) [CAS 1339058-04-6]
Hypidone (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.