Idebenone-13C, d3 [CAS 1189907-75-2]
Idebenone-13C, d3 [CAS 1189907-75-2]
SKU:QM-0054482-01
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Product Details
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Description
Idebenone-13C, d3 is the deuterium labeled and 13C-labeled Idebenone. Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier.
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CAS Number
[1189907-75-2]
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Molecular Formula
C18 13CH27D3O5
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Molecular Weight
342.45
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Smiles
O=C(C(CCCCCCCCCCO)=C(C1=O)C)C(OC)=C1O[13C]([2H])([2H])[2H]
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Target
Apoptosis; Isotope-Labeled Compounds; Mitochondrial Metabolism
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Shipping Conditions
Room temperature
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Idebenone-13C, d3 [CAS 1189907-75-2]
Idebenone-13C, d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.