1
/
of
1
IHMT-PI3K-455 [CAS 3047746-40-4]
IHMT-PI3K-455 [CAS 3047746-40-4]
SKU:QM-0068409
Price on request
Quantity
Request quote or documents
![IHMT-PI3K-455 [CAS 3047746-40-4]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
IHMT-PI3K-455 (Compound 15u) is a potent, selective, orally active PI3Kγ/δ dual inhibitor with IC50s of 7.1 nM and 0.57 nM for PI3Kγ and PI3Kδ, respectively. IHMT-PI3K-455 suppresses the AKT phosphorylation. IHMT-PI3K-455 inhibits tumor growth by recruiting and activating more CD8+ killing T cells.IHMT-PI3K-455 is used in cancer research[1].
-
CAS Number
[3047746-40-4]
-
Molecular Formula
C26H21F2N7O3
-
Molecular Weight
517.49
-
Smiles
COC1=C(OC)N=CC(C2=NC3=CC(NC4=CC=CC(CNC(C5=C(F)C=CC=C5F)=O)=N4)=NN3C=C2)=C1
-
Target
PI3K
-
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
-
Solubility
10 mM in DMSO
-
Shipping Conditions
Room temperature
Related Products
- QM-0015916 Wee1/HDAC-IN-1 [CAS 3037071-29-4]
- QM-0013795-01 Vizenpistat [CAS 2687222-58-6]
- QM-0008932 VEGFR-IN-7 [CAS 683235-33-8]
- QM-0008931 VEGFR-IN-6 [CAS 683235-34-9]
- QM-0008885 VEGFR/PDGFR-IN-1 [CAS 342785-98-2]
- QM-0008364-01 Verubecestat (Standard) [CAS 1286770-55-5]
- QM-0007272 Zavondemstat (sodium) [CAS 2908753-07-9]
- QM-0002491-01 Ziritaxestat (Standard) [CAS 1628260-79-6]
- QM-0002017 Zabadinostat (Standard) [CAS 934828-12-3]
- QM-0079654-01 Zabadinostat [CAS 934828-12-3]
Other industry favorites
- QM-0015916 Wee1/HDAC-IN-1 [CAS 3037071-29-4]
- QM-0013795-01 Vizenpistat [CAS 2687222-58-6]
- QM-0154836-01 Verdiperstat [CAS 890655-80-8]
- QM-0142135-01 Virstatin [CAS 88909-96-0]
- QM-0081849-01 Vorinostat (Standard) [CAS 149647-78-9]
- QM-0070505 VEGFR2-IN-3 [CAS 417717-09-0]
- QM-0081529-01 Ziritaxestat [CAS 1628260-79-6]
- QM-0205620-01 VEGFR-3/FLT4, Mouse (HEK293, hFc)
- QM-0178627-01 VinylMyristate (stabilizedwithMEHQ) [CAS 5809-91-6]
- QM-0175073-01 [Nle8] Somatostatin (1-28) (TFA)
IHMT-PI3K-455 [CAS 3047746-40-4]
IHMT-PI3K-455 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.