Imatinib-13C, d3
Imatinib-13C, d3
SKU:QM-0007605
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Product Details
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Description
Imatinib-13C, d3 (STI571-13C, d3) is 13C labeled Imatinib. Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5].
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Molecular Formula
C29 13CH31D3N7O
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Molecular Weight
512.65
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Smiles
O=C(C1=CC=C(CN2CC[N]CC2)C=C1)NC3=CC=C(C)C(NC4=NC(C5=CN=CC=C5)=CC=N4)=C3.C[13C]([2H])([2H])[2H]
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Target
Autophagy; Bcr-Abl; c-Kit; Isotope-Labeled Compounds; PDGFR; SARS-CoV
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Shipping Conditions
Room temperature
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Imatinib-13C, d3
Imatinib-13C, d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.