Imatinib (Standard) [CAS 152459-95-5]
Imatinib (Standard) [CAS 152459-95-5]
SKU:QM-0130312-01
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Product Details
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Description
Imatinib (Standard) is the analytical standard of Imatinib. This product is intended for research and analytical applications. Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5].
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CAS Number
[152459-95-5]
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Molecular Formula
C29H31N7O
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Molecular Weight
493.6
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Smiles
CN(CC1)CCN1CC2=CC=C(C(NC3=CC=C(C)C(NC4=NC(C5=CC=CN=C5)=CC=N4)=C3)=O)C=C2
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Target
Autophagy; Bcr-Abl; c-Kit; PDGFR; Reference Standards; SARS-CoV
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Shipping Conditions
Room temperature
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Hazard Statement
H341-H351-H360-H362
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Precautions
P260-P263-P264-P270-P280-P405-P501
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Imatinib (Standard) [CAS 152459-95-5]
Imatinib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.