Indomethacin-d4 Methyl Ester [CAS 1217064-61-3]
Indomethacin-d4 Methyl Ester [CAS 1217064-61-3]
SKU:QM-0148092-01
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Product Details
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Description
Indomethacin-d4 Methyl Ester is the deuterium labeled Indomethacin. Indomethacin (Indometacin) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells[1]. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes[2].
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CAS Number
[1217064-61-3]
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Molecular Formula
C20H14D4ClNO4
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Molecular Weight
375.84
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Smiles
O=C(C1=C([2H])C([2H])=C(C([2H])=C1[2H])Cl)N2C3=CC=C(OC)C=C3C(CC(OC)=O)=C2C
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Target
Autophagy; COX
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Purity
98.38
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Indomethacin-d4 Methyl Ester [CAS 1217064-61-3]
Indomethacin-d4 Methyl Ester is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.