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Indotecan (hydrochloride) [CAS 1228035-68-4]

Indotecan (hydrochloride) [CAS 1228035-68-4]

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SKU:QM-0087749-01

£392.63 GBP
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  • Description

    Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis[1][2].

  • CAS Number

    [1228035-68-4]

  • Molecular Formula

    C26H27ClN2O7

  • Molecular Weight

    514.95

  • Smiles

    O=C1C2=C(C3=C1C4=CC(OC)=C(C=C4C(N3CCCN5CCOCC5)=O)OC)C=C6OCOC6=C2.Cl

  • Target

    Topoisomerase

  • Purity

    99.8

  • Solubility

    DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

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5 mgQM-0087749-01
5 mgQM-0087749-01
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10 mgQM-0087749-02
10 mgQM-0087749-02
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25 mgQM-0087749-03
25 mgQM-0087749-03
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Indotecan (hydrochloride) [CAS 1228035-68-4]

Indotecan (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.