Inosine-5'-diphosphate-15N4 (dilithium)
Inosine-5'-diphosphate-15N4 (dilithium)
SKU:QM-0167669
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Product Details
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Description
Inosine-5'-diphosphate-15N4 dilithium (IDP-15N4 dilithium) is 15N labeled Inosine-5'-diphosphate dilithium. Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM) . Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research[1][2][3][4].
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Molecular Formula
C10H12Li2 15N4O11P2
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Molecular Weight
444.03
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Smiles
O=C1C2=C([15N]([C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(O[Li])(O[Li])=O)(O)=O)O3)C=[15N]2)[15NH]C=[15N]1
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Target
Apoptosis; c-Myc; Isotope-Labeled Compounds
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Inosine-5'-diphosphate-15N4 (dilithium)
Inosine-5'-diphosphate-15N4 (dilithium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.