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IQ-1S (free acid) [CAS 23146-22-7]
IQ-1S (free acid) [CAS 23146-22-7]
SKU:QM-0079176-01
£78.82 GBP
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Product Details
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Description
IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.
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CAS Number
[23146-22-7]
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Molecular Formula
C15H9N3O
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Molecular Weight
247.25
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Smiles
O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2
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Target
JNK
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Isoform
JNK1; JNK2; JNK3
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Purity
99.28
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Solubility
DMSO : 16.67 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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IQ-1S (free acid) [CAS 23146-22-7]
IQ-1S (free acid) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.