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Ivacaftor-13C6

Ivacaftor-13C6

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SKU:QM-0005623

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  • Description

    Ivacaftor-13C6 (VX-770-13C6) is 13C labeled Ivacaftor. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.

  • Molecular Formula

    C2013C6H30N2O3

  • Molecular Weight

    424.48

  • Smiles

    O=C(/C(C(C)=O)=C/NC)NC1=CC(O)=C(C(C)(C)C)C=C1C(C)(C)C.[13C]2=[13C][13C]=[13C][13C]=[13C]2

  • Target

    Autophagy; CFTR; Isotope-Labeled Compounds

  • Shipping Conditions

    Room temperature

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Ivacaftor-13C6

Ivacaftor-13C6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.