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JAK1-IN-14
JAK1-IN-14
SKU:QM-0073369
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Product Details
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Description
JAK1-IN-14 (Compound 12a) is a potent and selective JAK1 inhibitor. JAK1-IN-14 inhibits JAK1 and JAK2 with an IC50 value of 12.6 nM and 135 nM. JAK1-IN-14 suppresses hepatic fibrosis levels and can be used for the research of liver fibrosis and inflammatory diseases[1].
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Molecular Formula
C20H30N6O
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Molecular Weight
370.49
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Smiles
CN(C1CCN(CC(N2CCC(C)CC2)=O)CC1)C3=C4C(NC=C4)=NC=N3
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Target
JAK
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Isoform
JAK1; JAK2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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JAK1-IN-14
JAK1-IN-14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.