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JAK3/BTK-IN-6 [CAS 2243136-03-8]
JAK3/BTK-IN-6 [CAS 2243136-03-8]
SKU:QM-0067544
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Product Details
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Description
JAK3/BTK-IN-6 (compound 14h) is a potent BTK and JAK3 dual inhibitor, with IC50 values of 0.6 and 0.4 nM, respectively. JAK3/BTK-IN-6 shows good metabolic stability in human liver microsome. JAK3/BTK-IN-6 can be used for hematological and immune diseases research[1].
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CAS Number
[2243136-03-8]
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Molecular Formula
C21H17BF3N5O3
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Molecular Weight
455.2
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Smiles
C=CC(NC1=CC(NC2=C(C=NC(NC3=CC=C4B(OCC4=C3)O)=N2)C(F)(F)F)=CC=C1)=O
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Target
Btk; JAK
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Isoform
JAK1; JAK2; JAK3; Tyk2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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JAK3/BTK-IN-6 [CAS 2243136-03-8]
JAK3/BTK-IN-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.