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JAK3-IN-14 [CAS 454234-24-3]
JAK3-IN-14 [CAS 454234-24-3]
SKU:QM-0151837-01
£740.12 GBP
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Product Details
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Description
JAK3-IN-14 (compound 1) is a potent JAK3 inhibitor, with IC50 values of 38 and 600 nM for JAK3 and JAK2, respectively. JAK3-IN-14 shows inhibitory of IL-4 and IL-3 induced TF-1 cell proliferation, with IC50 values of 600 and 500 nM, respectively[1].
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CAS Number
[454234-24-3]
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Molecular Formula
C18H13N3O
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Molecular Weight
287.32
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Smiles
O=C1NC2=CC=C(C3=CN=CC=C3)C=C2/C1=C/C4=CC=CN4
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Target
JAK
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Isoform
JAK2; JAK3
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Purity
99.32
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Solubility
DMSO : 125 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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JAK3-IN-14 [CAS 454234-24-3]
JAK3-IN-14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.