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JAK3-IN-17
JAK3-IN-17
SKU:QM-0011671
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Quantity
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Product Details
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Description
JAK3-IN-17 (Compound X15) is an orally active JAK3 inhibitor (IC50: 14.56 nM) . JAK3-IN-17 inhibits the production of IL-2 and IL-6 in a DNCB-induced mouse atopic dermatitis model and exhibits anti-inflammatory activity[1].
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Molecular Formula
C21H15FN4O
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Molecular Weight
358.37
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Smiles
O=C(C=C)NC1=CC=CC(C2=CN=C3C=CC(C4=C(F)N=CC=C4)=CN32)=C1
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Target
JAK
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Isoform
JAK3
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Shipping Conditions
Room temperature
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JAK3-IN-17
JAK3-IN-17 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.