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JNJ-28312141 (hydrochloride) [CAS 1149939-55-8]
JNJ-28312141 (hydrochloride) [CAS 1149939-55-8]
SKU:QM-0006147
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Product Details
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Description
JNJ-28312141 hydrochloride is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 hydrochloride inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 hydrochloride exhibits anti-inflammatory activity in mouse arthritis model[1].
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CAS Number
[1149939-55-8]
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Molecular Formula
C26H33ClN6O2
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Molecular Weight
497.03
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Smiles
O=C(C1=NC(C#N)=CN1)NC2=C(C3=CCCCC3)C=C(C4CCN(C(CN(C)C)=O)CC4)C=C2.Cl
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Target
C-Fms
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Shipping Conditions
Room temperature
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JNJ-28312141 (hydrochloride) [CAS 1149939-55-8]
JNJ-28312141 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.