JNJ-39758979 (Standard) [CAS 1046447-90-8]
JNJ-39758979 (Standard) [CAS 1046447-90-8]
SKU:QM-0002227
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Product Details
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Description
JNJ-39758979 (Standard) is the analytical standard of JNJ-39758979. This product is intended for research and analytical applications. JNJ-39758979, a chemical probe, is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity[1][2].
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CAS Number
[1046447-90-8]
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Molecular Formula
C11H19N5
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Molecular Weight
221.31
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Smiles
NC1=NC(C(C)C)=CC(N2C[C@H](N)CC2)=N1
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Target
Histamine Receptor; Reference Standards
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Shipping Conditions
Room temperature
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JNJ-39758979 (Standard) [CAS 1046447-90-8]
JNJ-39758979 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.