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K145 (hydrochloride) [CAS 1449240-68-9]

K145 (hydrochloride) [CAS 1449240-68-9]

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QM-0152394-01

£118.38 GBP
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Product Details

  • Description

    K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity[1].

  • CAS Number

    [1449240-68-9]

  • Molecular Formula

    C18H25ClN2O3S

  • Molecular Weight

    384.92

  • Smiles

    O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2.[H]Cl

  • Target

    Apoptosis; SphK

  • Isoform

    SphK2

  • Concentration

    10mM

  • Purity

    99.63

  • Solubility

    DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0152394-01
5 mgQM-0152394-01
£118.38/ea		 £0.00
£118.38/ea £0.00
10 mM - 1 mLQM-0152394-02
10 mM - 1 mLQM-0152394-02
£127.38/ea		 £0.00
£127.38/ea £0.00
10 mgQM-0152394-03
10 mgQM-0152394-03
£212.81/ea		 £0.00
£212.81/ea £0.00
25 mgQM-0152394-04
25 mgQM-0152394-04
£379.26/ea		 £0.00
£379.26/ea £0.00
50 mgQM-0152394-05
50 mgQM-0152394-05
£543.29/ea		 £0.00
£543.29/ea £0.00
100 mgQM-0152394-06
100 mgQM-0152394-06
£791.15/ea		 £0.00
£791.15/ea £0.00
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K145 (hydrochloride) [CAS 1449240-68-9]

K145 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.