K777 (tosylate) [CAS 502960-91-0]
K777 (tosylate) [CAS 502960-91-0]
SKU:QM-0139570
Request quote or documents
![K777 (tosylate) [CAS 502960-91-0]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
K777 tosylate is a potent, orally active and irreversible cysteine protease inhibitor. K777 tosylate is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 tosylate irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 tosylate is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 tosylate inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively[1][2][3].
-
CAS Number
[502960-91-0]
-
Molecular Formula
C39H46N4O7S2
-
Molecular Weight
746.94
-
Smiles
O=S(O)(C1=CC=C(C=C1)C)=O.O=S(/C=C/[C@H](CCC2=CC=CC=C2)NC([C@@H](NC(N3CCN(CC3)C)=O)CC4=CC=CC=C4)=O)(C5=CC=CC=C5)=O
-
Target
Cathepsin; CCR; Cytochrome P450; Filovirus; Parasite; SARS-CoV
-
Shipping Conditions
Room temperature
Related Products
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052686-01 β-Phenyl GHB (sodium) [CAS 40951-19-7]
- QM-0052524 β-Nicotinamide mononucleotide, reduced form (disodium) (Standard) [CAS 108347-85-9]
- QM-0052354-01 ω-azido-C6 Ceramide [CAS 2108102-18-5]
- QM-0051720-01 β-Phenylethyl β-D-glucoside [CAS 18997-54-1]
- QM-0048489-01 β-N-methylamino-L-alanine (hydrochloride) (Standard) [CAS 16012-55-8]
- QM-0022874 β-Prumycin hydrochloride [CAS 54612-74-7]
- QM-0206006 β-Nicotinamide adenine dinucleotide reduced (dipotassium) [CAS 104809-32-7]
- QM-0204726-01 β-Nicotinamide mononucleotide, reduced form (disodium) [CAS 108347-85-9]
- QM-0204366-01 β-N-methylamino-L-alanine (hydrochloride) [CAS 16012-55-8]
Other industry favorites
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052686-01 β-Phenyl GHB (sodium) [CAS 40951-19-7]
- QM-0054913 β-D-Galactopyranose,2,3,4,6-tetrakis-O- (phenylmethyl),1-acetate [CAS 3866-62-4]
- QM-0054858-01 α-D-Mannopyranosyl chloride, 2,3,4,6-tetraacetate [CAS 14257-40-0]
- QM-0016946-01 β-Carboline-1-carboxylic acid [CAS 26052-96-0]
- QM-0016203 β-D-Glu-benzylalcohol-di (amide-C2) -mal
- QM-0178574-01 β-Sitosterol acetate, 40% (contains Campesterol acetate) [CAS 915-05-9]
- QM-0168310-01 γ-Linolenyl alcohol [CAS 24149-05-1]
- QM-0050582 β-D-Galaltosamine (hydrochloride) [CAS 14257-79-5]
- QM-0049152-01 β-keto Phentermine (hydrochloride) [CAS 6946-08-3]
K777 (tosylate) [CAS 502960-91-0]
K777 (tosylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.