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KDM5A-IN-1 (Standard) [CAS 1905481-36-8]

KDM5A-IN-1 (Standard) [CAS 1905481-36-8]

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SKU:QM-0001632

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  • Description

    KDM5A-IN-1 (Standard) is the analytical standard of KDM5A-IN-1. This product is intended for research and analytical applications. KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B).

  • CAS Number

    [1905481-36-8]

  • Molecular Formula

    C15H22N4O2

  • Molecular Weight

    290.37

  • Smiles

    O=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2

  • Target

    Histone Demethylase; Reference Standards

  • Shipping Conditions

    Room temperature

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KDM5A-IN-1 (Standard) [CAS 1905481-36-8]

KDM5A-IN-1 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.