L-2-Hydroxyglutaric acid (Standard) [CAS 13095-48-2]
L-2-Hydroxyglutaric acid (Standard) [CAS 13095-48-2]
SKU:QM-0094963
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Product Details
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Description
L-2-Hydroxyglutaric acid (Standard) is the analytical standard of L-2-Hydroxyglutaric acid. This product is intended for research and analytical applications. L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].
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CAS Number
[13095-48-2]
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Molecular Formula
C5H8O5
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Molecular Weight
148.11
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Smiles
O=C(O)[C@@H](O)CCC(O)=O
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Target
Endogenous Metabolite; Histone Demethylase; Mitochondrial Metabolism; Reference Standards
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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L-2-Hydroxyglutaric acid (Standard) [CAS 13095-48-2]
L-2-Hydroxyglutaric acid (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.