L-750667 (triHydrochloride) [CAS 1021868-80-3]
L-750667 (triHydrochloride) [CAS 1021868-80-3]
SKU:QM-0082463-01
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Product Details
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Description
L-750667 triHydrochloride is a selective antagonist for the D4 dopamine receptor, with a Ki value of 0.51 nM. The radiolabeled form of L-750667, [125I]L-750,667, has a Kd value of 0.16 nM for the D4 receptor. L-750667 triHydrochloride can reverse dopamine-induced inhibition of cAMP accumulation. It can be used to study the distribution and function of D4 dopamine receptors in the central nervous system and has potential applications in the fields of neuroscience and psychiatry[1][2].
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CAS Number
[1021868-80-3]
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Molecular Formula
C18H22Cl3IN4
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Molecular Weight
527.66
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Smiles
IC1=CC=C(C=C1)N2CCN(CC2)CC3=CNC4=NC=CC=C43.[H]Cl.[H]Cl.[H]Cl
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Target
Dopamine Receptor
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Isoform
D4 Receptor
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Purity
99.39
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Solubility
DMSO : 8.33 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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L-750667 (triHydrochloride) [CAS 1021868-80-3]
L-750667 (triHydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.