Lacidipine-13C4
Lacidipine-13C4
SKU:QM-0087293
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Product Details
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Description
Lacidipine-13C4 is 13C labeled Lacidipine. Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)[2].
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Molecular Formula
C22 13C4H33NO6
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Molecular Weight
459.51
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Smiles
O=[13C]([13C]1=C(C)NC(C)=[13C]([13C](OCC)=O)C1C2=CC=CC=C2/C=C/C(OC(C)(C)C)=O)OCC
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Target
Apoptosis; Calcium Channel; Caspase; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Lacidipine-13C4
Lacidipine-13C4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.