Lacidipine-13C8 [CAS 1261432-01-2]
Lacidipine-13C8 [CAS 1261432-01-2]
SKU:QM-0074900
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Product Details
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Description
Lacidipine-13C8 is the deuterium labeled Lacidipine[1]. Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI) [2][3].
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CAS Number
[1261432-01-2]
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Molecular Formula
C18 13C8H33NO6
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Molecular Weight
463.48
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Smiles
CCO[13C]([13C]1=[13C](N[13C]([13CH3])=[13C](C1C2=C(/C=C/C(OC(C)(C)C)=O)C=CC=C2)[13C](OCC)=O)[13CH3])=O
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Target
Apoptosis; Calcium Channel; Caspase; Reactive Oxygen Species (ROS)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Lacidipine-13C8 [CAS 1261432-01-2]
Lacidipine-13C8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.